Wnt蛋白家族7B抗体
规格：1mg/1ml
英文名： WNT7B
别名： Protein Wnt-7b; Wingless related MMTV integration site 7B; Wingless type MMTV integration site family member 7B; WNT7B; WNT7B_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human WNT7B
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit,
细胞定位：细胞外基质 分泌型蛋白
Wnt蛋白家族7B抗体产品介绍：background: Wnt7b is a secreted glycosylated protein that belongs to the Wnt family. Wnt proteins can be lipid modified and are ligands for members of the frizzled family of receptors, which mediate cell-cell communication during development. Wnt7b is thought to modulate several important signaling pathways in the lung which results in the coordinated proliferation of adjacent epithelial and mesenchymal cells to stimulate organ growth. Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Subunit: Interacts with PORCN (By similarity). Subcellular Location: Secreted, extracellular space, extracellular matrix. Wnt蛋白家族7B抗体Tissue Specificity: Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in ***** brain, lung and prostate. Post-translational modifications: Palmitoylation at Ser-206 is required for efficient binding to frizzled receptors. It is also required for subsequent palmitoylation at Cys-73. Palmitoylation is necessary for proper trafficking to cell surface (By similarity). Similarity:Wnt蛋白家族7B抗体 Belongs to the Wnt family Gene ID: 7477 Database links: Entrez Gene: 7477 Human Omim: 601967 Human SwissProt: P56706 Human Unigene: 512714 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产Wnt蛋白家族7B抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 干细胞 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid