血小板源性生长因子受体β样蛋白抗体
规格：1mg/1ml
英文名： PDGFRL
别名： PDGF receptor beta like tumor suppressor; PGFRL_HUMAN; PDGFR-like protein; PDGRL; PRLTS.
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDGFRL
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：
血小板源性生长因子受体β样蛋白抗体产品介绍：background: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer. Subunit: Forms a complex composed of PDGFRL, TNK2 and GRB2. Subcellular Location: Secreted (Probable). Tissue Specificity: Expressed in colon, lung and liver. DISEASE: Colorectal cancer (CRC) [MIM:114500]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum. Genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. Note=The gene represented in this entry is involved in disease pathogenesis. Note=A polymorphism in PDGFRL has been reported to be associated with susceptibility to Behcet disease (PubMed:19815557). Behcet disease is a 血小板源性生长因子受体β样蛋白抗体complex multiple-system disorder characterized by recurrent oral ulcerations, recurrent genital ulcerations, typical skin lesions, and uveitis. Behcet disease also involves joints, blood vessels, musculoskeletal, neurological systems, and the gastrointestinal tract. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Gene ID: 5157 Database links: Entrez Gene: 5157 Human Entrez Gene: 68797 血小板源性生长因子受体β样蛋白抗体Mouse Entrez Gene: 515017 Cow GenBank: NP_006198.1 Human Omim: 604584 Human SwissProt: Q5BIP2 Cow SwissProt: Q15198 Human SwissProt: Q2PFX1 Monkey SwissProt: Q6PE55 Mouse Unigene: 458573 Human Unigene: 284246 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板源性生长因子受体β样蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid