神经细胞凋亡调节转化蛋白1抗体
规格：1mg/1ml
英文名： NARC1/PCSK9
别名： FH3; HCHOLA3; Hypercholesterolemia autosomal dominant 3; NARC 1; NARC-1; NARC1; Neural apoptosis regulated convertase 1; Neural apoptosis-regulated convertase 1; PC 9; PC9; PCSK 9; PCSK9; PCSK9_HUMAN;
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCSK9/NA
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
神经细胞凋亡调节转化蛋白1抗体产品介绍：background: May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis. Function: The precursor protein but not the mature protein may form multimers. Subunit: The precursor protein but not the mature protein may form multimers. Subcellular Location: Secreted. Tissue Specificity: Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. Post-translational modifications: The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.神经细胞凋亡调节转化蛋白1抗体 Similarity: Belongs to the peptidase S8 family. Contains 1 peptidase S8 domain. Database links: Entrez Gene: 101132967 Gorilla Entrez Gene: 255738 Human Entrez Gene: 100102 Mouse Entrez Gene: 298296 Rat Omim: 607786 Human SwissProt: A8T650 Gorilla SwissProt: Q8NBP7 Human SwissProt: Q80W65 Mouse SwissProt: P59996 Rat Unigene: 18844 Human Unigene: 133268 Mouse Unigene: 19195神经细胞凋亡调节转化蛋白1抗体 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 前蛋白转化酶枯草溶菌素9(PCSK9)是近年来新发现的一种与调节脂质代谢密切相关的基因,编码前蛋白转化酶NARC-1。Narc-1/pcsk9可通过调节细胞表面的低密度脂蛋白受体(LDLR)水平,参与脂质代谢,从而在动脉粥样硬化性**的发生、发展中发挥重要作用。
神经细胞凋亡调节转化蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 神经生物学 信号转导 干细胞 细胞凋亡 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid