溶酶体丝氨酸蛋白酶DPP2抗体
规格:1mg/1ml
英文名: DPP2
别名: Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; DPP2; DPP7; DPPII; QPP; Quiescent cell proline dipeptidase.
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DPP2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆 分泌型蛋白
溶酶体丝氨酸蛋白酶DPP2抗体产品介绍:background: DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels,溶酶体丝氨酸蛋白酶DPP2抗体 and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients. Function: Plays an important role in the degradation of some oligopeptides. Subunit: Homodimer. Subcellular Location: Lysosome. Cytoplasmic vesicle. Secreted. Tissue Specificity: Detected in溶酶体丝氨酸蛋白酶DPP2抗体 seminal plasma (at protein level). Post-translational modifications: N-glycosylated. Similarity: Belongs to the peptidase S28 family. Gene ID: 29952 Database links: Entrez Gene: 29952 Human Entrez Gene: 83768 Mouse Entrez Gene: 83799 Rat Omim: 610537 Human SwissProt: Q9UHL4 Human SwissProt: Q9ET22 Mouse SwissProt: Q9EPB1 Rat Unigene: 37916 Human Unigene: 3363 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶酶体丝氨酸蛋白酶DPP2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid