细胞维甲酸结合蛋白2抗体
规格：1mg/1ml
英文名： CRABP2
别名： Cellular retinoic acid binding protein 2; Cellular retinoic acid binding protein II; CRABP II; CRABPII; CRABP 2; CRABP-2; RBP6; RABP2_HUMAN.
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRABP2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig,
细胞定位：细胞核 细胞浆
细胞维甲酸结合蛋白2抗体产品介绍：background: A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. Function: Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. Subunit: Interacts with RXR and RARA. Interacts with importin alpha. Subcellular Location: Cytoplasm. Endoplasmic reticulum. Nucleus. Post-translational modifications: Sumoylated in 细胞维甲酸结合蛋白2抗体response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Gene ID: 1382 Database links: Entrez Gene: 1382 Human Entrez Gene: 12904 Mouse Entrez Gene: 29563 Rat Omim: 180231 Human SwissProt: P29373 Human SwissProt: P22935 Mouse SwissProt: P51673 Rat 细胞维甲酸结合蛋白2抗体Unigene: 405662 Human Unigene: 4757 Mouse Unigene: 11333 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞维甲酸结合蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid