**特异性解旋酶抗体
规格：1mg/1ml
英文名： HELLS
别名： Helicase lymphoid specific; HELLS; HELLS_HUMAN; LSH; Lymphoid specific helicase; Lymphoid-specific helicase; Nbla10143; PASG; Proliferation associated SNF2 like protein; Proliferation-associated SNF2-
分子量： 97kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SMARCA6/
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：
**特异性解旋酶抗体产品介绍：background: SMARCA6 gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Function: Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity). Subcellular Location: Nucleus (By similarity). Note=Closely associated with pericentric heterochromatin (By similarity). Tissue Specificity: Highly expressed in proliferative tissues such as ***** thymus and testis, and expressed at lower levels in uterus,**特异性解旋酶抗体 small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloid and lymphoid leukemias. Similarity: Belongs to the SNF2/RAD54 helicase family. Contains 1 helicase ATP-binding domain.**特异性解旋酶抗体 Contains 1 helicase C-terminal domain. Gene ID: 3070 Database links: Entrez Gene: 3070 Human Entrez Gene: 15201 Mouse GenBank: AAH30963 Human Omim: 603946 Human SwissProt: Q9NRZ9 Human SwissProt: Q60848 Mouse Unigene: 655830 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**特异性解旋酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid