氧化蛋白质水解酶
规格：1mg/1ml
英文名： AARE
别名： AARE; ACPH; Acyl peptide hydrolase; Acylamino acid releasing enzyme; Acylaminoacyl peptidase; APEH; APH; D3F15S2; D3S48E; DNF15S2; N acylaminoacyl peptide hydrolase; OPH; Oxidized protein hydrolase; A
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AARE
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
氧化蛋白质水解酶产品介绍：background: AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated氧化蛋白质水解酶 peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Subunit: Interacts with SUV420H1, SUV420H2 and USP4 Subcellular Location: Nucleus. Similarity: Belongs to the retinoblastoma protein (RB) family. Gene ID: 327 Database links: Entrez Gene: 327 Human Entrez Gene: 235606 Mouse Entrez Gene: 24206 Rat GenBank: 33875348 氧化蛋白质水解酶Human Omim: 102645 Human SwissProt: P13798 Human SwissProt: Q8R146 Mouse SwissProt: P13676 Rat Unigene: 517969 Human Unigene: 219639 Mouse Unigene: 11057 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
氧化蛋白质水解酶产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid