细胞周期蛋白依赖性激酶抑制剂2D抗体
规格：1mg/1ml
英文名： CDKN2D/p19 INK4d
别名： CDK inhibitor p19INK4d; CDKN2D; cell cycle inhibitor, Nur77 associating protein; Cyclin dependent kinase inhibitor 2D; Cyclin-dependent kinase 4 inhibitor D; Cyclin-dependent kinase inhibitor 2D (p19,
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CDKN2D/p
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
细胞周期蛋白依赖性激酶抑制剂2D抗体产品介绍：background: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as细胞周期蛋白依赖性激酶抑制剂2D抗体 spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]. Function: Interacts strongly with CDK4 and CDK6 and inhibits them. Subunit: Interacts with CDK6. Subcellular Location: Nucleus. Cytoplasm. Similarity: Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. Contains 4 ANK repeats. Database links: Entrez Gene: 510244 Cow Entrez Gene: 1032 Human Entrez Gene: 12581 Mouse Entrez Gene: 494444 Rat Omim: 600927 Human 细胞周期蛋白依赖性激酶抑制剂2D抗体SwissProt: Q29RV0 Cow SwissProt: P55273 Human SwissProt: Q60773 Mouse Unigene: 435051 Human Unigene: 29020 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞周期蛋白依赖性激酶抑制剂2D抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 染色质和核信号 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid