早幼粒细胞白血病锌指蛋白抗体
规格：1mg/1ml
英文名： Plzf
别名： Promyelocytic leukemia zinc finger protein; ZBT16_HUMAN; ZBTB16; Zfp145; Zinc finger and BTB domain containing 16; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145 (Kruppel li
分子量： 74kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Plzf (60
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：细胞核
早幼粒细胞白血病锌指蛋白抗体产品介绍：background: Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Function: Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Subunit: Binds EPN1. Interacts with ZBTB32 and CUL3. Subcellular Location: Nucleus. Tissue Specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the早幼粒细胞白血病锌指蛋白抗体 kidney and lung. DISEASE: Defects in ZBTB16 are the cause of skeletal defects genital hypoplasia and mental retardation (SGYMR) [MIM:612447]. A disorder characterized by mental retardation, craniofacial dysmorphism, microcephaly and short stature. Additional features include absence of the thumbs, hypoplasia of the radii and ulnae, additional vertebrae and ribs, retarded bone age and genital 早幼粒细胞白血病锌指蛋白抗体hypoplasia. Note=A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 BTB (POZ) domain. Contains 9 C2H2-type zinc fingers. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
早幼粒细胞白血病锌指蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 发育生物学 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid