DNA修复和重组蛋白RAD54B抗体
规格：1mg/1ml
英文名： RAD54B
别名： DNA repair and recombination protein RAD54B; Fibrinogen silencer binding protein; FSBP; RAD54 homolog B; RA54B_HUMAN.
分子量： 103kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RAD54B
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：
DNA修复和重组蛋白RAD54B抗体产品介绍：background: The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. Function: Involved in DNA repair and mitotic recombination. May play an active role in recombination processesDNA修复和重组蛋白RAD54B抗体 in concert with other members of the RAD52 epistasis group. Subunit: Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect. Subcellular Location: Nucleus (Probable). Tissue Specificity: Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon. Similarity: Belongs to the SNF2/RAD54 helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicaseDNA修复和重组蛋白RAD54B抗体 C-terminal domain. Database links: UniProtKB/Swiss-Prot: Q9Y620.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA修复和重组蛋白RAD54B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 染色质和核信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid