血管生成素样蛋白3抗体
规格:1mg/1ml
英文名: ANGPTL3
别名: ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; ANGPTL3; FHBL
分子量: 49kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ANG5/ANG
交叉反应:Human, Mouse, Rat, Cow, Rabbit,
细胞定位:分泌型蛋白
血管生成素样蛋白3抗体产品介绍:background: Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen 血管生成素样蛋白3抗体(FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes. Subcellular Location: Secreted血管生成素样蛋白3抗体 Tissue Specificity: Expressed principally in liver. Weakly expressed in kidney. Similarity: Contains 1 fibrinogen C-terminal domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血管生成素样蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 **学 信号转导 生长因子和** 血管内皮细胞 新陈代谢
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid