钙网蛋白抗体
规格:1mg/1ml
英文名: Calreticulin
别名: Autoantigen RO; CALR; CALR protein; CALR_HUMAN; Calregulin; Calreticulin; cC1qR; CRP55; CRTC; Endoplasmic reticulum resident protein 60; ERp60; grp60; HACBP; RO; Sicca syndrome antigen A; SSA.
分子量: 44kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Calretic
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞浆 细胞膜 细胞外基质 分泌型蛋白
钙网蛋白抗体产品介绍:background: Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Subunit: Monomer. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Interacts with PDIA3/ERp57 (By similarity). Interacts with NR3C1 and TRIM21. Interacts with GABARAP. Subcellular Location: Endoplasmic reticulum lumen. Cytoplasm, 钙网蛋白抗体cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Similarity: Belongs to the calreticulin family. Gene ID: 811 Database links: Entrez Gene: 41166 Fruit fly (Drosophila melanogaster) Entrez Gene: 811 Human Entrez Gene: 12317 Mouse Entrez Gene: 100009050 Rabbit Entrez Gene: 64202 Rat Omim: 109091 Human SwissProt: P29413 Fruit fly (Drosophila melanogaster) SwissProt: P27797 Human SwissProt: P14211 钙网蛋白抗体Mouse SwissProt: P15253 Rabbit SwissProt: P18418 Rat Unigene: 2457 Fruit fly (Drosophila melanogaster) Unigene: 515162 Human Unigene: 1971 Mouse Unigene: 467043 Mouse Unigene: 974 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙网蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 细胞表面分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid