缺氧诱导因子脯氨酰4羟化酶抗体
规格：1mg/1ml
英文名： HIFPH4
别名： EGLN4; HIF prolyl hydroxylase PH4; HIF-PH4; HIF-prolyl hydroxylase 4; HIFPH4; HPH-4; Hypoxia inducible factor prolyl 4 hydroxylase; Hypoxia inducible factor prolyl hydroxylase; Hypoxia-inducible facto
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HIFPH4
交叉反应：Human, Mouse, Rat, Pig, Horse,
细胞定位：细胞膜
缺氧诱导因子脯氨酰4羟化酶抗体产品介绍：background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals缺氧诱导因子脯氨酰4羟化酶抗体 through PLCB2 and the calcium-regulated cation channel TRPM5. Subunit: Homodimer. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Post-translational modifications: Glycosylated. Similarity: Contains 2 EF-hand domains. 缺氧诱导因子脯氨酰4羟化酶抗体Contains 1 Fe2OG dioxygenase domain. Database links: UniProtKB/Swiss-Prot: Q9NXG6.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
缺氧诱导因子脯氨酰4羟化酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学 染色质和核信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid