单核细胞趋化诱导蛋白1抗体
规格:1mg/1ml
英文名: MCPIP1
别名: dJ423B22.1; MCP 1 treatment-induced protein; MCP-induced protein 1; MCPIP 1; MCPIP; Ribonuclease ZC3H12A; RP3-423B22.1; ZC12A_HUMAN; ZC3H 12A; ZC3H12 A; Zc3h12a; Zinc finger CCCH domain-containing pro
分子量: 66kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MCPIP1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
单核细胞趋化诱导蛋白1抗体细胞定位:细胞核 细胞浆
产品介绍:background: Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. Function: Has RNase activity and selectively degrades 单核细胞趋化诱导蛋白1抗体specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. Subcellular Location: Cytoplasm (By similarity). Nucleus. Similarity: Belongs to the ZC3H12 family. Contains 1 C3H1-type zinc finger. Database links: 单核细胞趋化诱导蛋白1抗体UniProtKB/Swiss-Prot: Q5D1E8.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
单核细胞趋化诱导蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 **学 染色质和核信号 信号转导 细胞凋亡 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid