成纤维细胞生长因子20抗体
规格:1mg/1ml
英文名: FGF20
别名: FGF-20; Fgf20; FGF20_HUMAN; FGFK; Fibroblast Growth Factor 20.
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FGF20.
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow,
细胞定位:分泌型蛋白
成纤维细胞生长因子20抗体产品介绍:background: The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq,成纤维细胞生长因子20抗体 Oct 2009]. Function: Neurotrophic factor that regulates central nervous development and function. Subunit: Homodimer. Interacts with FGFR2 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Predominantly expressed in the cerebellum. Similarity: Belongs to the heparin-binding growth factors family. Gene ID: 26281 Database links: Entrez Gene: 26281 Human Entrez Gene: 80857成纤维细胞生长因子20抗体 Mouse Entrez Gene: 66017 Rat Omim: 605558 Human SwissProt: Q9NP95 Human SwissProt: Q9ESL9 Mouse SwissProt: Q9EST9 Rat Unigene: 199905 Human Unigene: 425526 Mouse Unigene: 64492 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
成纤维细胞生长因子20抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 生长因子和**
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid