原癌基因酪氨酸蛋白激酶FES抗体
规格:1mg/1ml
英文名: FES
别名: c-fes/fps protein; cFES; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami; Feline sarcoma oncogene; FPS; Oncogene FES; Oncogene FES feline sarcoma virus; Proto oncogene tyrosine protein kinase F
分子量: 90kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FES
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:
原癌基因酪氨酸蛋白激酶FES抗体产品介绍:background: FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand,原癌基因酪氨酸蛋白激酶FES抗体 cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge,原癌基因酪氨酸蛋白激酶FES抗体 in part, by regulating the internalization and down-regulation of the TLR4 receptor complex. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原癌基因酪氨酸蛋白激酶FES抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid