卷曲螺旋结构域蛋白106抗体
规格:1mg/1ml
英文名: CCDC106
别名: Ccdc106; Coiled-coil domain-containing protein 106; Protein predicted by clone 23882; ZNF581; CC106_HUMAN.
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CCDC106
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位:细胞核
卷曲螺旋结构域蛋白106抗体产品介绍:background: Promotes the degradation of p53/TP53 protein and inhibits its transactivity. Function: Promotes the degradation of p53/TP53 protein and inhibits its transactivity. Subunit: Interacts with p53/TP53. Subcellular Location: Nucleus. Note=Colocalizes with p53/TP53. Gene ID: 29903 Database links: Entrez Gene: 29903 Human Entrez Gene: 卷曲螺旋结构域蛋白106抗体232821 Mouse Entrez Gene: 499071 Rat Omim: 613478 Human SwissProt: Q9BWC9 Human SwissProt: Q3ULM0 Mouse Unigene: 82482 Human Unigene: 482157 Mouse Unigene: 488775 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CCDC106通过与p53蛋白相互作用,促进p53蛋白的降解,卷曲螺旋结构域蛋白106抗体导致p53功能失活。CCDC106基因很可能是一个癌基因,CCDC106的高表达可能是导致具有野生型p53肿瘤发生的原因之一。
卷曲螺旋结构域蛋白106抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 细胞周期蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid