磷酸化非受体型蛋白酪氨酸磷酸酶7抗体
规格：1mg/1ml
英文名： phospho-PTPN7 (Ser246)
别名： PTPN7(phospho S246); BPTP 4; BPTP4; Dual specificity phosphatase 1; Hematopoietic protein tyrosine phosphatase; LC PTP; LCPTP; LPTP; Protein tyrosine phoshatase non receptor type stress induced; Prote
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated Synthesised phosphopeptide derived from human
交叉反应：Mouse, Rat,
细胞定位：
磷酸化非受体型蛋白酪氨酸磷酸酶7抗体产品介绍：background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]. Function: Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T 磷酸化非受体型蛋白酪氨酸磷酸酶7抗体and B-lymphocyte development and signal transduction. Subunit: Monomer. Interacts with MAPK1, MAPK3 and several other MAP kinases. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed exclusively in thymus and spleen. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 5778 Human Entrez Gene: 320139 Mouse Entrez Gene: 246781 Rat Omim: 176889 Human SwissProt: P35236 Human SwissProt:磷酸化非受体型蛋白酪氨酸磷酸酶7抗体 Q8BUM3 Mouse SwissProt: P49445 Rat Unigene: 402773 Human Unigene: 258388 Mouse Unigene: 10160 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化非受体型蛋白酪氨酸磷酸酶7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid