磷脂转移蛋白抗体
规格:1mg/1ml
英文名: PLTP
别名: HDLCQ9; High density lipoprotein cholesterol level quantitative trait locus 9, included; Lipid transfer protein II; OD107; Phospholipid transfer protein; Plasma phospholipid transfer protein; PLTP_HUM
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PLTP C-t
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位:
磷脂转移蛋白抗体产品介绍:background: The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Function: Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein磷脂转移蛋白抗体 remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability. Subcellular Location: Secreted. Tissue Specificity: Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver >磷脂转移蛋白抗体 skeletal muscle > brain. Similarity: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. Database links: UniProtKB/Swiss-Prot: P55058.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷脂转移蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 转录调节因子 细胞膜受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid