Bcl-2结合抑凋亡蛋白2抗体
规格:1mg/1ml
英文名: BAG2
别名: BAG 2; BAG-2; BAG family molecular chaperone regulator 2; BAG-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; dJ417I1.2; KIAA0576; MGC1
分子量: 24kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human BAG2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞浆
Bcl-2结合抑凋亡蛋白2抗体产品介绍:background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the Bcl-2结合抑凋亡蛋白2抗体ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]. Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Similarity: Contains 1 BAG domain. Database links:Bcl-2结合抑凋亡蛋白2抗体 Entrez Gene: 9532 Human Omim: 603882 Human SwissProt: O95816 Human Unigene: 55220 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Bcl-2结合抑凋亡蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 细胞凋亡 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid