磷酸二羟丙酮?；泼缚固?/strong>
规格：1mg/1ml
英文名： GNPAT
别名： DAPAT; DHAPAT; Acyl CoA dihydroxyacetonephosphateacyltransferase; DAP AT; DHAP AT; Dihydroxyacetone phosphate acyltransferase; EC 2.3.1.42; Glyceronephosphate O acyltransferase; OTTHUMP00000036147.
分子量： 38, 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GNPAT
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
磷酸二羟丙酮?；泼缚固?/strong>产品介绍：background: GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Subunit: May be part of an heterotrimeric complex composed of DAP-AT, ADAP-S and a modified form of DAP-AT. 磷酸二羟丙酮?；泼缚固?/strong>Subcellular Location: Peroxisome membrane; Peripheral membrane protein; Matrix side. Note=Exclusively localized to the lumenal side of the peroxisomal membrane. DISEASE: Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2) [MIM:222765]. RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and 磷酸二羟丙酮?；泼缚固?/strong>severe mental retardation. Similarity: Belongs to the GPAT/DAPAT family. Database links: Entrez Gene: 8443 Human Entrez Gene: 14712 Mouse Omim: 602744 Human SwissProt: O15228 Human SwissProt: P98192 Mouse Unigene: 498028 Human Unigene: 29114 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸二羟丙酮?；泼缚固?/strong>产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid