胆盐激活脂肪酶抗体
规格：1mg/1ml
英文名： Bile salt-activated lipase
别名： BAL; Bile salt-stimulated lipase; BSDL; BSSL; Bucelipase; Carboxyl ester lipase (bile salt stimulated lipase); Carboxyl ester lipase; CEase; CEL; CELL; Cholesterol esterase; FAP; FAPP; Fetoacinar panc
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Bile sal
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：分泌型蛋白
胆盐激活脂肪酶抗体产品介绍：background: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat(VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by 胆盐激活脂肪酶抗体RefSeq]. Function: Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides. Subcellular Location: Secreted. Tissue Specificity: Mammary gland and pancreas. DISEASE: Defects in CEL are a cause of maturity-onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:609812]; also known as diabetes and pancreatic exocrine 胆盐激活脂肪酶抗体dysfunction (DPED). MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early *****hood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. Similarity: Belongs to the type-B carboxylesterase/lipase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胆盐激活脂肪酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid