CD8β链（CD8-β）抗体
规格：1mg/1ml
英文名： CD8B
别名： CD8b antigen; T cell surface glycoprotein CD8 beta chain; CD8 antigen beta polypeptide 1 (p37); CD8 antigen beta polypeptide 1; CD8 beta; CD8b; CD8b molecule; CD8B_HUMAN; CD8B1; Leu2; Ly3; LYT3; MGC11
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD8B
交叉反应：Human, Mouse, Rat, Chicken, Pig, Horse, Guinea Pig,
细胞定位：细胞膜 分泌型蛋白
CD8β链（CD8-β）抗体产品介绍：background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Function: Identifies cytotoxic/suppressorCD8β链（CD8-β）抗体T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Subunit: In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Subcellular Location: Isoform 1, 2, 4, 5:Cell membrane; Single-pass type I membrane protein. Isoform 3, 6, 7, 8: Secreted. Tissue Specificity: Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ TCD8β链（CD8-β）抗体-cells. Expression of isoform 6 is higher in peripheral CD8+ T-cells than in thymus CD8+ T-cells. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 926 Database links: Entrez Gene: 926 Human Entrez Gene: 12526 Mouse Omim: 186730 Human SwissProt: P10966 Human SwissProt: P10300 Mouse Unigene: 405667 Human Unigene: 333148 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD8β链（CD8-β）抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized