热休克蛋白B2抗体
规格：1mg/1ml
英文名： HSPB2
别名： DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from hu HSPB2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
热休克蛋白B2抗体产品介绍：background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, 热休克蛋白B2抗体suggesting that HSPB2 may be an important factor in tumor transformation and metastasis. Function: May regulate the kinase DMPK. Subunit: Interacts with DMPK; may enhance its kinase activity. Subcellular Location: Cytoplasm. Nucleus. Localizes to nuclear foci. Tissue Specificity: Expressed preferentially in skeletal muscle and heart. Similarity: Belongs to the small heat shock protein (HSP20) family. Database links: Entrez 热休克蛋白B2抗体Gene: 508671 Cow Entrez Gene: 611362 Dog Entrez Gene: 100736126 Guinea pig Entrez Gene: 101828097 Hamster Entrez Gene: 3316 Human Entrez Gene: 69253 Mouse Entrez Gene: 100520143 Pig Entrez Gene: 161476 Rat Omim: 602179 Human SwissProt: Q16082 Human SwissProt: Q99PR8 Mouse SwissProt: O35878 Rat Unigene: 709660 Human Unigene: 1980 Mouse Unigene: 22486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
热休克蛋白B2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid