黑色素瘤相关抗原11抗体
规格:1mg/1ml
英文名: MAGEA11
别名: Cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; CT1.11; MAGE 11; MAGE 11 antigen; MAGAB_HUMAN; MAGE11; MAGEA 11; Melanoma antigen family A 11; Melanoma associated antigen 11; MG
分子量: 48kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MAGEA11
交叉反应:Human,
细胞定位:细胞核 细胞浆
黑色素瘤相关抗原11抗体产品介绍:background: MAGEA11 (Melanoma antigen family A, 11) is a member of the MAGEA gene family. MAGEA proteins are expressed in melanomas and other cancers. MAGEA11 acts as androgen receptor co-regulator increasing androgen receptor activity by modulating the receptors interdomain interaction. Function: Acts as androgen receptor co-regulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor 黑色素瘤相关抗原11抗体transformation or aspects of tumor progression. Subcellular Location: Nucleus. Cytoplasm. Tissue Specificity: Expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma. 黑色素瘤相关抗原11抗体Expressed in testis, ovary, prostate, cancerous prostate, breast and adrenal tissue. Similarity: Contains 1 MAGE domain. Database links: UniProtKB/Swiss-Prot: P43364.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产黑色素瘤相关抗原11抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号 信号转导 肿瘤细胞生物标志物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid