CD161c抗体
规格：1mg/1ml
英文名： CD161c
别名： CD161 antigen like family member C; CD161 antigen-like family member C; CD161c; Killer cell lectin like receptor subfamily A member 1C; Killer cell lectin like receptor subfamily B member 1C; Klrb1c;
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse CD161/NK
交叉反应：Mouse, Rat,
CD161c抗体细胞定位：细胞膜
产品介绍：background: NK1.1, a member of the NKRPI family of cell surface receptors, is a type II integral membrane protein with a C type lectin domain. It is expressed as a disulfide linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. Subunit:CD161c抗体 Homodimer; disulfide-linked. Interacts with acid phingomyelinase/SMPD1. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in ***** T-cells with a memory antigenic phenotype. Similarity: Contains 1 C-type lectin domain. Gene ID: CD161c抗体100043861 Database links: Entrez Gene: 3820 Human Entrez Gene: 100043861 Mouse Entrez Gene: 362443 Rat Omim: 602890 Human SwissProt: Q12918 Human SwissProt: Q0ZUP1 Mouse SwissProt: Q0ZUP0 Rat Unigene: 169824 Human Unigene: 66911 Mouse Unigene: 198693 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD161c抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 细胞膜受体 自然杀伤细胞 t-**细胞 上皮细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid