大鼠细小病毒H-1株(H-1)抗体
规格：1mg/1ml
英文名： Capsid protein VP1
别名： Parvovirus h-1 coat; CAPSD_PAVHH; Capsid protein VP1; Coat protein VP1.
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse Capsid p
交叉反应：Murine minute virus (H-1 parvovirus)
细胞定位：
大鼠细小病毒H-1株(H-1)抗体产品介绍：Function: Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.大鼠细小病毒H-1株(H-1)抗体 Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity). Subcellular大鼠细小病毒H-1株(H-1)抗体 Location: Virion (By similarity). Host nucleus (Potential). Similarity: Belongs to the parvoviridae capsid protein family. Database links: UniProtKB/Swiss-Prot: P03136.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 大鼠H-1病毒株是由Toolan(1960)从经大鼠传代的人肿瘤细胞系(HEP-1)分离到得第2株大鼠细小病毒(RPV),通常称为H-1病毒,又称Toolan病毒。
大鼠细小病毒H-1株(H-1)抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 **及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid