ATP结合盒转运家族蛋白13抗体
规格：1mg/1ml
英文名： ABCC13
别名： ATP binding cassette protein C13; ATP binding cassette, sub family C (CFTR/MRP), member 13; C21orf73; PRED6.
分子量： 31kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ABCC13
交叉反应：Human,
细胞定位：细胞核
ATP结合盒转运家族蛋白13抗体产品介绍：background: This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] Function: This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ATP结合盒转运家族蛋白13抗体This family member is part of the MRP subfamily, which is involved in multi drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. It is expressed at its highest level in fetal liver and fetal spleen. In the *****, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood leukocytes. There are five named isoforms. Subcellular Location: Nucleus; integral to membrane. Tissue Specificity: Highest expression in fetal liver and fetal spleen. In the *****, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood lATP结合盒转运家族蛋白13抗体eukocytes. Similarity: Belongs to the binding-protein-dependent transport system permease family. Contains 1 ABC transmembrane type-1 domain. Database links: Entrez Gene: 150000 Human Omim: 608835 Human SwissProt: Q9NSE7 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ATP结合盒转运家族蛋白13抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 转录调节因子 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid