NUDT7蛋白抗体
规格:1mg/1ml
英文名: NUDT7
别名: Nucleoside diphosphate linked moiety X motif 7; Nudix (nucleoside diphosphate linked moiety X) type motif 7; Nudix motif 7; Nudix type motif 7; NUDT 7; NUDT7; Peroxisomal coenzyme A diphosphatase NUDT
分子量: 27kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NUDT7
交叉反应:Human, Mouse, Rat, Rabbit,
细胞定位:
NUDT7蛋白抗体产品介绍:background: NUDT7 is a member of the Nudix hydrolase family. It is a Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. It has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. It may be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Function: Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or NUDT7蛋白抗体thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity). Subcellular Location: Peroxisome. Tissue Specificity: Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta. Weakly expressed in brain. Similarity: Belongs to the Nudix hydrolase family. PCD1 subfamily. Contains 1 nudix hydrolase domain. Database links: Entrez Gene: NUDT7蛋白抗体283927 Human Entrez Gene: 67528 Mouse Entrez Gene: 361413 Rat Omim: 609231 Human SwissProt: P0C024 Human SwissProt: Q99P30 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NUDT7蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 神经生物学 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid