锌指蛋白769抗体
规格:1mg/1ml
英文名: ZNF769/RB associated KRAB repressor
别名: RB associated KRAB repressor; hRBaK; Hypothetical protein RBAK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger protein; RBAK; RBAK_HUMAN; Zinc finger prot
分子量: 83kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF769
交叉反应:Human, Mouse, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞核
锌指蛋白769抗体产品介绍:background: This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011] Function:锌指蛋白769抗体 May repress E2F-dependent transcription. May promote AR-dependent transcription. Subcellular Location: Nucleus. Tissue Specificity: Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 16 C2H2-type zinc fingers. Contains 1 KRAB domain. Gene ID: 57786 Database links: Entrez Gene: 57786 Human Entrez Gene: 锌指蛋白769抗体57782 Mouse Omim: 608191 Mouse SwissProt: Q9NYW8 Human SwissProt: Q8BQC8 Mouse Unigene: 396178 Human Unigene: 320419 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白769抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid