烟碱型乙酰胆碱受体β2抗体
规格：1mg/1ml
英文名： CHRNB2
别名： Nicotinic Acetylcholine Receptor beta 2; Acetylcholine receptor beta 2 neural; ACHB2_HUMAN; ACHN; Acrb 2; Acrb2; b2 nAchR; Cholinergic receptor nicotinic beta 2; Cholinergic receptor nicotinic beta po
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHRNB2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位：细胞膜
烟碱型乙酰胆碱受体β2抗体产品介绍：background: Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008] Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Subunit: Neuronal AChR is composed of two different types of subunits: alpha and 烟碱型乙酰胆碱受体β2抗体beta. Beta-2 subunit can be combined to alpha-2, alpha-3 or alpha-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; 烟碱型乙酰胆碱受体β2抗体Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-2/CHRNB2 sub-subfamily. Gene ID: 1141 Database links: Entrez Gene: 1141 Human Entrez Gene: 11444 Mouse Entrez Gene: 54239 Rat Omim: 118507 Human SwissProt: P17787 Human SwissProt: Q9ERK7 Mouse SwissProt: P12390 Rat Unigene: 2306 Human Unigene: 35088 Mouse Unigene: 53978 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
烟碱型乙酰胆碱受体β2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid