5-三磷酸肌醇受体2抗体
规格:1mg/1ml
英文名: ITPR2
别名: 4; 5-trisphosphate receptor; Inositol 1 4 5 trisphosphate receptor type 2; Inositol 1,4,5-trisphosphate receptor type 2; Inositol 145 trisphosphate receptor type 2; InsP3 R2; InsP3R2; IP3 R2; IP3 rece
分子量: 308kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ITPR2
交叉反应:Human, Mouse, Rat, Cow,
细胞定位:细胞浆 细胞膜
5-三磷酸肌醇受体2抗体产品介绍:background: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. Function: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). Subunit: Homotetramer. Interacts with CABP1. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Isoform 5-三磷酸肌醇受体2抗体Short is found in skeletal muscle and heart. Post-translational modifications: Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release. Similarity: Belongs to the InsP3 receptor family. Contains 5 MIR domains. Gene ID: 3709 Database links: Entrez Gene: 281878 Cow Entrez Gene: 3709 Human Entrez Gene: 16439 Mouse Entrez Gene: 81678 Rat Omim: 600144 Human SwissProt5-三磷酸肌醇受体2抗体: Q8WN96 Cow SwissProt: Q14571 Human SwissProt: Q9Z329 Mouse SwissProt: P29995 Rat Unigene: 512235 Human Unigene: 393003 Mouse Unigene: 7800 Mouse Unigene: 89152 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
5-三磷酸肌醇受体2抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid