葡萄糖转运蛋白8抗体
规格：1mg/1ml
英文名： GLUT8
别名： Glucose Transporter 8; Glucose transporter type 8; Glucose transporter type X1; GLUT-8; GLUT 8; GLUTX1; SLC2A8; solute carrier family 2 (facilitated glucose transporter) member 8.
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GLUT8
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
葡萄糖转运蛋白8抗体产品介绍：background: Glucose transporter 8 is an insulin-regulated facilitative glucose transporter. It binds cytochalasin B in a glucose-inhibitable manner. It appears to be a dual-specific sugar transporter as it can be inhibited by fructose. It is highly expressed in testis, where it is down-regulated by estrogen, but not in testicular carcinoma. Lower amounts are present in most other tissues. Subunit: Interacts with AP2B1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. Insulin induces a change in the intracellular localization and gives rise to insertion in the plasma membrane. 葡萄糖转运蛋白8抗体Tissue Specificity: Highest level of expression in placenta and testis. Highly expressed in ***** and pubertal testis, but not prepubertal testis. Lower levels of expression in brain, liver, heart, kidney, fat and skeletal muscle. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. Database links: Entrez Gene: 29988 Human Entrez Gene: 56017 葡萄糖转运蛋白8抗体Mouse Entrez Gene: 85256 Rat Omim: 605245 Human SwissProt: Q9NY64 Human SwissProt: Q9JIF3 Mouse SwissProt: Q9JJZ1 Rat Unigene: 179522 Human Unigene: 305754 Mouse Unigene: 12923 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
葡萄糖转运蛋白8抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid