异质核糖核蛋白F抗体
规格:1mg/1ml
英文名: hnRNP F
别名: Heterogeneous nuclear ribonucleoprotein F; Heterogeneous nuclear ribonucleoprotein F; hnRNP F; HNRNPF; hnRP F; hnRPF; mcs94 1; MGC110997; Nucleolin like protein; Nucleolin like protein mcs94 1; OK/SW
分子量: 46kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human hnRNP F
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:
异质核糖核蛋白F抗体产品介绍:background: hnRNP F is part of the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. hnRNP F binds to RNAs which have guanosine-rich sequences. Function: Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of异质核糖核蛋白F抗体 alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. Subunit: Identified in the spliceosome C complex. Interacts with AGO1, AGO2, TBP and TXNL4/DIM1. Subcellular Location: Nucleus, nucleoplasm. 异质核糖核蛋白F抗体Tissue Specificity: Expressed ubiquitously. Post-translational modifications: Sumoylated. Similarity: Contains 3 RRM (RNA recognition motif) domains. Database links: UniProtKB/Swiss-Prot: P52597.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异质核糖核蛋白F抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 染色质和核信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid