副肿瘤综合症小脑变性相关蛋白抗体
规格：1mg/1ml
英文名： HuC
别名： ELAV (embryonic lethal abnormal vision Drosophila) like 3; ELAV-like protein 3 isoform 1; ELAV-like protein 3; Hu antigen C; ELAV like protein 3; ELAVL3; Hu antigen C; HUC; HUCL; Paraneoplastic cerebe
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ELAVL3/H
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：
副肿瘤综合症小脑变性相关蛋白抗体产品介绍：background: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]. Function: Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA.副肿瘤综合症小脑变性相关蛋白抗体 May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Tissue Specificity: Brain specific. Similarity: Belongs to the RRM elav family. Contains 3 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 1995 Human Entrez Gene: 15571 Mouse Entrez Gene: 282824 Rat Omim: 603458 Human SwissProt: Q14576 Human SwissProt: Q60900 Mouse 副肿瘤综合症小脑变性相关蛋白抗体Unigene: 1701 Human Unigene: 390167 Mouse Unigene: 22586 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
副肿瘤综合症小脑变性相关蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid