磷酸丙糖异构酶抗体
规格：1mg/1ml
英文名： Triosephosphate isomerase
别名： TIM; TPI 1; TPI; TPI1; Triose phosphate isomerase 1; Triose phosphate isomerase; Triosephosphate isomerase 1; Triosephosphate isomerase; MGC88108; TPIS_HUMAN.
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Trioseph
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
磷酸丙糖异构酶抗体产品介绍：background: This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq] Subunit: Homodimer. Post-translational modifications: The initiator methionine for isoform 2 is removed. DISEASE: Triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]: Autosomal 磷酸丙糖异构酶抗体recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the triosephosphate isomerase family. Gene ID: 7167 Database links: UniProtKB/Swiss-Prot: P60174.3 Entrez Gene: 281543 Cow Entrez Gene: 7167 Human Entrez Gene: 21991 Mouse Entrez Gene: 24849 Rat Omim: 磷酸丙糖异构酶抗体190450 Human SwissProt: Q5E956 Cow SwissProt: P54714 Dog SwissProt: P60174 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 磷酸丙糖异构酶（Triose-phosphate isomerase，通常简称为TPI或TIM）是一种能够催化丙糖磷酸异构体在二羟丙酮磷酸和D型甘油醛-3-磷酸之间转换。 磷酸丙糖异构酶在糖酵解中具有重要作用，对于有效的能量生成是必不可少的。磷酸丙糖异构酶被发现存在于几乎所有的生物体，包括哺乳动物、昆虫、**、植物和大多数**中。 如果人体缺乏磷酸丙糖异构酶，会导致严重的神经系统紊乱，该病症被称为磷酸丙糖异构酶缺乏症。
磷酸丙糖异构酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-100 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid