线粒体二羧酸载体蛋白抗体
规格:1mg/1ml
英文名: SLC25A10
别名: Mitochondrial dicarboxylate carrier; DIC; SLC25A10; Solute carrier family 25 member 10; DIC_HUMAN.
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC25A10
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:
线粒体二羧酸载体蛋白抗体产品介绍:background: The mitochondrial dicarboxylate carrier protein (mDIC) belongs to superfamily of mitochondrial transporters. It has been demonstrated that the expression of mDIC leads to hyperpolarization of the mitochondria, as well as succinate uptake by the mitochondria. It is highly expressed in adipose tissue, where its expression is downregulated by insulin and upregulated by free fatty acids. mDIC is also thought to play a role in glyceroneogenesis. Function: Involved in translocation of malonate, malate 线粒体二羧酸载体蛋白抗体and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. Tissue Specificity: Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed. Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family. Contains 3 Solcar 线粒体二羧酸载体蛋白抗体repeats. Database links: UniProtKB/Swiss-Prot: Q9UBX3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体二羧酸载体蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号 转录调节因子 线粒体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid