葡萄糖-6磷酸脱氢酶抗体
规格：1mg/1ml
英文名： Glucose 6 Phosphate Dehydrogenase
别名： G6PD; G6PD_HUMAN; G6PD1; G6pdx; Glucose 6 phosphate 1 dehydrogenase; Glucose-6-phosphate 1-dehydrogenase; MET19; POS10; Zwf1p.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Glucose
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
细胞定位：
葡萄糖-6磷酸脱氢酶抗体产品介绍：background: Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) . Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity. Function: Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. Subunit: Homodimer or homotetramer. Tissue Specificity: Isoform Long is found in lymphoblasts, granulocytes and sperm. DISEASE: Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) [MIM:305900]. Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles葡萄糖-6磷酸脱氢酶抗体 have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity. Similarity: Belongs to the glucose-6-phosphate dehydrogenase family. Gene ID: 2539 Database links: Entrez Gene: 2539 Human Entrez Gene: 14381 Mouse Entrez Gene: 24377 Rat Omim: 305900 Human SwissProt: P11413 Human SwissProt: Q00612 Mouse SwissProt: P05370 Rat Unigene: 461047 Human Unigene: 684904 Human Unigene:葡萄糖-6磷酸脱氢酶抗体27210 Mouse Unigene: 11040 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. G-6-PD（Glucose-6-phosphate Dehydrogenase）。一种存在於人体红血球内，协助葡萄糖进行新陈代谢之酵素，在这代谢过程中会产生一种叫NADPH的物质能以?；ず煅蛎馐苎趸镏实耐?。 G6PD缺乏时，若身体接触到具氧化性的特定物质或服用了这类**，红血球就容易被破坏而发生急性溶血反应。
葡萄糖-6磷酸脱氢酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid