胰高血糖素受体抗体
规格：1mg/1ml
英文名： Glucagon Receptor
别名： GCGR; GGR; GL R; GL-R; GLR; GLR_HUMAN; MGC138246; Glucagon receptor precursor.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Glucagon
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Guinea Pig, G
细胞定位：细胞膜
胰高血糖素受体抗体产品介绍：background: The physiologic effects of glucagon are mediated through the glucagon receptor, a member of the superfamily of receptors characterized by a 7-transmembrane domain structure and by their coupling via GTP-binding proteins (G proteins) to adenyl cyclase. The glucagon receptor has been reported to be expressed in liver and adipose, but not in adrenal medulla. ESTs have been isolated from liver/spleen and kidney libraries. Function: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by 胰高血糖素受体抗体G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in fetal tissues, including testis, adrenal gland, 胰高血糖素受体抗体brain, white blood cells and brain. Similarity: Belongs to the G-protein coupled receptor 2 family. Database links: UniProtKB/Swiss-Prot: P47871.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰高血糖素受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞膜受体 糖尿病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid