滋养层细胞抗原3β-HSD抗体
规格:1mg/1ml
英文名: HSD3B1
别名: 3 beta and steroid delta isomerase 1; 3 beta and steroid hydroxy delta 5 steroid dehydrogenase; 3 beta HSD I; 3BH; 3BHSD; HGNC:5217; HSD3B; HSD3B1; HSDB3; HSDB3A; Hydroxy delta 5 steroid dehydrogenase
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSD3B1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位:细胞浆 细胞膜
滋养层细胞抗原3β-HSD抗体产品介绍:background: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Tissue Specificity: Placenta and skin. Predominantly expressed in mammary gland tissue. Similarity: 滋养层细胞抗原3β-HSD抗体Belongs to the 3-beta-HSD family. Gene ID: 3283 Database links: Entrez Gene: 3283 Human Entrez Gene: 3284 Human Entrez Gene: 15492 Mouse Entrez Gene: 15494 Mouse Entrez Gene: 29632 Rat Entrez Gene: 360348 Rat Entrez Gene: 682974 Rat Omim: 109715 Human SwissProt: P14060 Human SwissProt: P26439 Human SwissProt: O35469 Mouse SwissProt: P24815 Mouse SwissProt: P26149 Mouse 滋养层细胞抗原3β-HSD抗体SwissProt: P26150 Mouse SwissProt: P22071 Rat SwissProt: P22072 Rat SwissProt: Q5FVK0 Rat SwissProt: Q62878 Rat Unigene: 364941 Human Unigene: 654399 Human Unigene: 140811 Mouse Unigene: 14435 Mouse Unigene: 158717 Mouse Unigene: 482364 Mouse Unigene: 109394 Rat Unigene: 128814 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HSD3B1属于滋养层细胞标记物(也包括hPL、hCG、Mel-CAN、p63、HLA—G、CK18和inhibin-α) 在很多肿瘤及正常***组织中表达也很高。
滋养层细胞抗原3β-HSD抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid