羟基类固醇脱氢酶11β1抗体
规格:1mg/1ml
英文名: HSD11B1
别名: 11 beta HSD 1; 11 beta HSD1; 11 beta hydroxysteroid dehydrogenase 1; 11 DH; 11DH; Corticosteroid 11 beta dehydrogenase isozyme 1; HDL; HSD 11; HSD11; HSD11B; HSD11L; Hydroxysteroid (11 beta) dehydroge
分子量: 32kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSD11B1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞浆 细胞膜
羟基类固醇脱氢酶11β1抗体产品介绍:background: HSD11B1 is a microsomal enzyme that catalyses the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyse the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. Subunit: Homodimer.羟基类固醇脱氢酶11β1抗体 Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Tissue 羟基类固醇脱氢酶11β1抗体Specificity: Widely expressed. Highest expression in liver. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
羟基类固醇脱氢酶11β1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 转录调节因子 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid