过氧化还原酶5/6抗体
规格:1mg/1ml
英文名: PRDX5+PRDX6
别名: 1 Cys; 1 Cys peroxiredoxin; 1 Cys PRX; 1 cysPrx; 24 kDa protein; Acidic calcium independent phospholipase A2; aiPLA2; Antioxidant protein 2; AOP2; Aop2 rs3; Brp 12; Ciliary body glutathione peroxidase
分子量: 18/25kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Peroxire
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞浆
过氧化还原酶5/6抗体产品介绍:background: Peroxiredoxin (Prx) is in the peroxidase family, whose mammalian members have been known to contribute to cell proliferation, differentiation and apoptosis. Many isoforms (about 50 proteins), collected in accordance with amino acid sequence homology, particularly the amino terminal region containing active site cysteine residue, and the thiol specific antioxidant activity, distribute throughout all the kingdoms. Mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes have the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in molecular过氧化还原酶5/6抗体 size and vary in subcellularlocalization: PrxI, II, and VI in cytosol; PrxIII in mitochondria; PrxIV in ER and secretion; PrxV shows complicated distribution including peroxisome, mitochondria and cytosol. Subunit: Monomer. Subcellular Location: Mitochondrion. Cytoplasm. Peroxisome. Tissue Specificity: Widely expressed. Similarity: Belongs to the peroxiredoxin 2 family. Contains 1 thioredoxin domain. Database links: Entrez Gene: 9588 Human Entrez Gene: 11758 Mouse Entrez Gene: 94167 Rat Omim: 602316 Human SwissProt: P30041 Human SwissProt: O08709 Mouse SwissProt:过氧化还原酶5/6抗体 O35244 Rat Unigene: 120 Human Unigene: 186185 Mouse Unigene: 42 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
过氧化还原酶5/6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 细胞凋亡 干扰素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid