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产品名称: 生长分化因子15/巨嗜细胞抑制因子1抗体
产品型号: GDF15
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档
简单介绍
生长分化因子15/巨嗜细胞抑制因子1抗体应用于IHC、WB、 IF、IP、ELISA等科研实验，按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源，可将其分为天然抗体和**抗体。生长分化因子15/巨嗜细胞抑制因子1抗体生产每个流程都执行严格的检测标准，保证蛋白抗原产品质量，质量稳定，实验效果明显。
生长分化因子15/巨嗜细胞抑制因子1抗体
的详细介绍
生长分化因子15/巨嗜细胞抑制因子1抗体
规格：1mg/1ml
英文名： GDF15
别名： GDF 15; GDF-15 Growth differentiation factor 15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC 1; MIC-1; MIC1; NAG 1; NAG1; NRG 1; NRG1; NSAID (nonsteroidal anti inflammatory
分子量： 12.5/34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GDF-15
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
生长分化因子15/巨嗜细胞抑制因子1抗体产品介绍：background: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and ***** tissues. GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53. Subcellular Location: Secreted. Tissue 生长分化因子15/巨嗜细胞抑制因子1抗体Specificity: Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. Similarity: Belongs to the TGF-beta family. Database links: Entrez Gene: 9518 Human Omim: 605312 Human SwissProt: Q99988 Human Unigene: 616962 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or生长分化因子15/巨嗜细胞抑制因子1抗体 diagnostic applications. 生长分化因子15（GDF15）是骨形态发生蛋白（BMP）和转化生长因子-β超家族成员。GDF-15又叫巨噬细胞抑制因子（macrophage inhibiting cytokine，MIC）-1、胎盘转化生长因子 （placental transformation growth factor，PTGF）-β、前列腺衍生因子（prostate derived factor，PDF）和胎盘骨形态发生蛋白（placental bone morphogeneticprotein，PLAB）。 有学者认为：GDF-15在肿瘤发展的不同阶段发挥着不同的生物学作用；随着肿瘤的发**展，GDF-15可能表达不生长分化因子15/巨嗜细胞抑制因子1抗体同形式的蛋白，在肿瘤发生的早期阶段可能发挥抑瘤作用，而在肿瘤发展的后期阶段发挥促瘤作用。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 细胞凋亡 生长因子和** 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid