λ轻链抗体
规格:1mg/1ml
英文名: Lambda Light Chain
别名: Ig lambda chain C regions; Bence Jones protein; BJP; Constant region of lambda light chains; IGLC 1; IGLC 2; IGLC 3; IGLC; IGLC1; IGLC2; IGLC3; LAC1_HUMAN; Immunoglobulin lambda constant 1; Mcg marker
分子量: 22.5kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Lambda L
交叉反应:Human, Mouse, Rat,
λ轻链抗体细胞定位:分泌型蛋白
产品介绍:background: All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of theλ轻链抗体 constant region. Subcellular Location: Cytoplasmic Similarity: Contains 1 Ig-like (immunoglobulin-like) domainλ轻链抗体. Gene ID: 3535 Database links: Entrez Gene: 3535 Human Entrez Gene: 3546 Human Entrez Gene: 8217 Human Omim: 147220 Human SwissProt: P01701 Human SwissProt: P01842 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 该抗体特异识别**球蛋白λ轻链,可用于鉴定白血病、浆细胞瘤以及某些非霍奇金氏**瘤。这些肿瘤的共同特征是只限于单个轻链的表达,因此轻链Kappa和Lamda可用于良恶性**病变(反应性**细胞增生和**瘤)的辅助性诊断。
λ轻链抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid