k轻链抗体
规格：1mg/1ml
英文名： Ig kappa chain C region
别名： Kappa Light Chain; IGKC; HCAK 1; HCAK1; Ig kappa chain C region; IGKC; Immunoglobulin kappa constant; Immunoglobulin kappa constant region; Immunoglobulin kappa light chain; Kappa 1 immunoglobulin lig
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：Purified human Kappa light chain
交叉反应：Human,
细胞定位：
k轻链抗体产品介绍：background: Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses.k轻链抗体 In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INVk轻链抗体 allotypic marker, Ala 45 and Leu 83. Gene ID: 3514 Database links: Entrez Gene: 3514 Human Omim: 147200 Human SwissProt: P01834 Human Unigene: 449609 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 该抗体特异识别人**球蛋白κ轻链，可用于鉴定白血病、浆细胞瘤以及某些非霍奇金氏**瘤。这些肿瘤的共同特征是只限于单个轻链的表达，因此轻链Kappa和Lamda可用于良恶性**病变（反应性**细胞增k轻链抗体生和**瘤）的辅助性诊断。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid