T**细胞CD1抗体
规格：1mg/1ml
英文名： CD1a
别名： CD1D; A1 domain; CD1A; CD1A antigen; CD1B; CD1b antigen; CD1b molecule; CD1C; CD1C antigen; CD1c molecule; CD1d molecule; Cd1d1; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Corti
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD1a
交叉反应：Human,
细胞定位：细胞浆 细胞膜 细胞外基质
T**细胞CD1抗体产品介绍：background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.T**细胞CD1抗体 [provided by RefSeq]. Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. Subcellular Location: Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. Tissue Specificity: Expressed on cortical thymocytes, epidermal T**细胞CD1抗体Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Gene ID: 909 Database links: Entrez Gene: 909 Human Omim: 188370 Human SwissProt: P06126 Human Unigene: 1309 Human Important Note: This product as supplied is intended for research use only, not for use T**细胞CD1抗体in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞表面分子 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid