磷酸化促凋亡Bik蛋白抗体
规格:1mg/1ml
英文名: phospho-Bik(Thr33)
别名: Bik (phospho T33); p-Bik (phospho T33); Apoptosis inducer NBK; BBC1; Bcl-2-interacting killer; BCL2 interacting killer; bhikhari; BIK; Bik-like killer protein; BIK_HUMAN; BIP 1; BIP1; BP 4; BP4; cb 60
分子量: 18kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human,
细胞定位:细胞膜
磷酸化促凋亡Bik蛋白抗体产品介绍:background: The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. Function: Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. Subunit: Interacts with RHBDL4/RHBDD1. Subcellular Location: Endomembrane system; Single-pass membrane protein. Mitochondrion 磷酸化促凋亡Bik蛋白抗体membrane; Single-pass membrane protein (By similarity). Note=Around the nuclear 磷酸化促凋亡Bik蛋白抗体envelope, and in cytoplasmic membranes. Post-translational modifications: Proteolytically cleaved by RHBDL4/RHBDD1. RHBDL4/RHBDD1-induced cleavage is a necessary step prior its degradation by the proteosome-dependent mechanism. Database links: UniProtKB/Swiss-Prot: Q13323.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化促凋亡Bik蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid