腺苷酸环化酶1抗体
规格：1mg/1ml
英文名： ADCY1
别名： 3'5' cyclic AMP synthetase; ADCY1; adenyl cyclase; Adenylate cyclase 1; adenylate cyclase type I; ATP pyrophosphate lyase; Brain adenylate cyclase 1; Ca(2+)/calmodulin activated adenylyl cyclase; EC 4
分子量： 123kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Adenylyl
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
腺苷酸环化酶1抗体产品介绍：background: The membrane bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein coupled receptors. Eight human AC isoforms (AC-1 through AC-4) have been identified up to now and genes for at least nine adenylate cyclase (AC-1-AC-9) have been cloned characterized and sequenced. This is a calmodulin-sensitive adenylyl cyclase which may be involved in regulatory processes in the central nervous system. It may play a role in neuronal plasticity, memory acquisition and learning and is expressed predominantly in the brain, retina and adrenal medulla. Function: This is a calmodulin-sensitive adenylyl cyclase. May be involved 腺苷酸环化酶1抗体in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Brain, retina and adrenal medulla. Similarity: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. Gene ID: 107 Database links: Entrez Gene: 107 Human Entrez Gene: 432530 Mouse 腺苷酸环化酶1抗体Omim: 103072 Human SwissProt: Q08828 Human SwissProt: O88444 Mouse Unigene: 192215 Human Unigene: 259733 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 腺苷酸环化酶(adenylate cyclase, AC) 是G蛋白偶联受体家族之一，是膜整合蛋白,它的氨基端和羧基端都朝向细胞质。AC在膜的细胞质面有两个催化结构域,还有两个膜整合区,每个膜整合区分别有6个跨膜的α螺旋。哺乳动物中已发现6个腺苷酸环化酶异构体。由于AC能够将ATP转变成cAMP,引起细胞的信号应答,因此,腺苷酸环化酶是G蛋白偶联系统中的效应物。
腺苷酸环化酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid