转录因子Brn3蛋白抗体Brn3α
规格：1mg/1ml
英文名： BRN3A
别名： Brain specific homeobox/POU domain protein 3A; Brn 3.0; BRN 3A; Brn3; Homeobox/POU domain protein RDC 1; Homeobox/POU domain protein RDC1; Oct T1; OctT1; POU Domain Class 4 Transcription Factor 1; POU
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BRN3A
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位：细胞核
转录因子Brn3蛋白抗体Brn3α产品介绍：background: This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some ***** acute myeloid leukemias. [provided by RefSeq, Mar 2012]. Function: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Subcellular 转录因子Brn3蛋白抗体Brn3αLocation: Nucleus. Tissue Specificity: Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye. DISEASE: Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth. Similarity: Belongs to the POU transcription factor family. Class-4 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. Database转录因子Brn3蛋白抗体Brn3α links: Entrez Gene: 5457 Human Entrez Gene: 18996 Mouse Entrez Gene: 114503 Rat Omim: 601632 Human SwissProt: Q01851 Human SwissProt: P17208 Mouse SwissProt: P20266 Rat Unigene: 654522 Human Unigene: 246550 Mouse Unigene: 232568 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 转录因子Brn3可能直接参与对轴突和树突生长能力的调控。
转录因子Brn3蛋白抗体Brn3α产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid