胎盘蛋白14抗体
规格：1mg/1ml
英文名： PP14
别名： Placental protein 14; alpha uterine protein; Pregnancy-associated endometrial alpha-2 globulin; GD; GdA; GdF; GdS; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PAEP protein; PEG; PEP; PP14; Pre
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Glycodel
交叉反应：Human,
细胞定位：分泌型蛋白
胎盘蛋白14抗体产品介绍：background: This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq, Jul 2008]. Function: 胎盘蛋白14抗体This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Subunit: Homodimer. Subcellular Location: Secreted. Post-translational modifications: At least two differentially glycosylated forms are found. Glycodelin-A (GdA) (amniotic fluid) with contraceptive and immunosuppressive activities and glycodelin-S (Gds) (seminal plasma) whose role is not yet known. The gender-specific glycosylation may serve to regulate key process involved in human reproduction. 胎盘蛋白14抗体Similarity: Belongs to the calycin superfamily. Lipocalin family. Gene ID: 5047 Database links: Entrez Gene: 5047 Human Omim: 173310 Human SwissProt: P09466 Human Unigene: 532325 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胎盘蛋白质14又称黄体****内膜癌相关蛋白。 胎盘蛋白质14是胎盘球蛋白的一种，该蛋白是**内膜分泌较高的黄体**，目前多用于**内膜癌的研究
胎盘蛋白14抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid